Kyrle Disease (Hyperkeratosis Follicularis and Parafollicularis in Cutem Penetrans; Hyperkeratosis Penetrans) 333j95d 333j95d 333j95d 333j95d 333j95d 333j95d 333j95d
General: Etiology unknown; associated in siblings, suggesting heredofamilial condition; syndrome may belong in the diabetic syndromes; rare skin disorder; onset usually in the third to sixth decades of life.
Ocular: Subcapsular cataracts; corneal changes characterized as minute, yellow-brown subepithelial opacities, noted to be more dense and more deeply penetrating in the peripheral cornea than in the central cornea.
Clinical: Multiple flesh-colored, horny papules associated with hair follicles.
Duane TD. Clinical Ophthalmology. Philadelphia: JB Lippincott, 1987.
Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981,467.
Sehgal VN, et al. Perforating dermatoses: a review and report of four cases. J Dermatol 1993; 20:329-340.
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Tilted Disk Syndrome 1 [...] |
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