Werlhof disease (hemophilia and thrombocytopenic purpura)

General: Hemorrhagic disease of unknown etiology.

Ocular: Retinal hemorrhages; degeneration or severe intraocular hemorrhages with resultant retinitis proliferans.

Clinical: Petechiae and ecchymoses of skin and mucous membranes; tendency to bruise; decreased level of circulating platelets with a normal clotting time.

Kobayashi H, Honda Y. Intraocular hemorrhage in a patient with hemophilia. Metab Ophthalmol 1985; 8:27-30.

Pau H. Differential diagnosis of eye diseases. New York: Thieme, 1987.

Werlhof PG. Disquisitio Medica et Philogica de Variolis et Anthracibus. Brunswick: 1735.