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Temporal arteritis syndrome (cranial arteritis syndrome; giant cell arteritis; hutchinson-horton-magath-brown syndrome)


Temporal Arteritis Syndrome (Cranial Arteritis Syndrome; Giant Cell Arteritis; Hutchinson-Horton-Magath-Brown Syndrome) 313g68d 313g68d 313g68d 313g68d 313g68d 313g68d

General: Etiology unknown; mainly females; mainly whites; ages 55 to 80 years; temporal artery shows inflammatory thickening; arteritis of the vessels supplying the optic nerve.

Ocular: Transient ptosis; partial or complete loss of vision on the affected side; retinal detachment; exudates and hemorrhages; narrowing of retinal vessels; obstruction of the central retinal artery; optic atrophy; ischemic optic neuropathy; acute decreased intraocular pressure; corneal hypesthesia; palsies of extraocular muscles; hemorrhagic glaucoma; diplopia; hemorrhages on or around the disk.

Clinical: Throbbing headache; hyperalgesia of the scalp; malaise; anorexia; weakness; weight loss; fever; nodular pulmonary nodules; cough; otitis with deafness.

Cullen JF, Coleiro JA. Ophthalmic complications of giant cell arteritis. Surv Ophthalmol 1976; 20:247-260.

Cullen JF. Occult temporal arteritis. Br J Ophthalmol 1967; 51:513.

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Healey LA, Wilske KR. Manifestations of giant cell arteritis. Med Clin North Am 1977; 61:261-270.

Sorensen S, Lorenzen I. Giant-cell arteritis, temporal arteritis and polymyalgia rheumatica. Acta Med Scand 1977; 201:207-213.

Zenone T, et al. Unusual manifestations of giant cell arteritis: pulmonary nodules, cough, conjunctivitis and otitis with deafness. Eur Respir J 1994; 7:2252-2254.




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