Pseudomonas aeruginosa infections

General: Gram-negative rod with secondary contaminant of superficial 636h73g wounds; Pseudomonas organisms produce a variety of enzymes that cause pathologic changes, including hemolysins and exotoxins as well as a glycocalyx that increases adherence.

Ocular: Hypopyon; conjunctivitis; keratitis; ulcerative abscess of cornea; endophthalmitis; panophthalmitis.

Clinical: Local tissue damage and diminished host resistance, which may occur in ear, lung, skin, and urinary tract.

Allen HF. Current status of prevention, diagnosis, and management of bacterial corneal ulcers. Ann Ophthalmol 1971; 3:235-246.

Cole GG, et al. Pseudomonas ophthalmia neonatorum: a cause of blindness. Br Med J 1980; 281:41-44.

Fraunfelder FT, Roy FH. Current Ocular Therapy. 5th ed. Philadelphia: WB Saunders, 2000.

Herbst RW. A guide to antibiotic therapy of ocular infections. Ophthalmol Surg 1972; 3:101-l20.