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Pigmentary ocular dispersion syndrome (pigmentary glaucoma)


Pigmentary Ocular Dispersion Syndrome (Pigmentary Glaucoma)

General: Polygenic inheritance; onset at average age 52 years; distribution of pigment in chambe 414c29e r angle; atrophy of posterior iris epithelium; most commonly affects young Caucasian males with myopia; mechanism is likely to be mechanical rubbing between iris pigment epithelium and packets of lens zonules, resulting in aqueous flow obstruction secondary to accumulation of pigment granules in the trabecular meshwork.

Ocular: Myopia; glaucomatous field changes; ocular hypertension; iris translucency; abnormal number of iris processes; insertion of iris anterior to scleral spur; pigmentation of posterior trabecular meshwork, grades 3 to 4; Krukenberg spindles; presence of pigmentation on equatorial border of lens capsule; glaucomatous cupping and myopic optic nerve changes.



Becker B, et al. The pigment dispersion syndrome. Am J Ophthalmol 1977; 83:161.

Farrar SM, Shields MB. Current concepts in pigmentary glaucoma. Surv Ophthalmol 1993; 37:233-252.

Jabbur NS; Tuli S; Barequet IS, et al. Outsome of laser in situ keratomileusis in patients with pigment dispersion syndrome. J Cataract Refract Surg 2004; 30: 110-l14.

Lehto I. Long-term prognosis of pigmentary glaucoma. Acta Ophthalmol 1991; 69:437-443.

Lunde MW. Argon laser trabeculoplasty in pigmentary dispersion syndrome with glaucoma. Am J Ophthalmol 1983; 96:721-725.

Richter CU, et al. Pigmentary dispersion syndrome and pigmentary glaucoma. Arch Ophthalmol 1986; 104:211-215.




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