P
e Syndrome (Hypertensive Diencephalic Syndrome)
General: Irritation of parasympathetic and sympathetic centers in diencephalon; intradermal histamine 0.25 mg reproduces syndrome; prognosis unpredictable; more frequent in women; onset age 18 to 30 years; spontaneous attacks lasting several minutes.
Ocular: Excessive lacrimation; arteriosclerotic and hypertensive fundus changes.
Clinical: Vasomotor blush over face, neck, and trunk, followed by perspiration; tachycardia; palpitations; elevated baseline blood pressure with additional 20 to 30 mm Hg rise during attacks; reduced respiration, perhaps labored; increased bowel sounds; salivation; sexual frigidity; tremor of hands and generalized tremulousness.
e IH. A syndrome simulating diencephalic stimulation occurring in patients with essential hypertension. Am J Med Sci 1935; 190:9.
Schroeder HA, Goldman ML. Test for the presence of the hypertensive diencephalic syndrome using histamine. Am J Med Sci 1949; 6:162.
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