Lubarsch-pick syndrome (primary amyloidosis; idiopathic amyloidosis; amyloidosis)

General: Rare condition of unknown etiology; inherited as a dominant trait, with male preponderance; c 333e49d haracterized by amyloid accumulation in muscles and in gastrointestinal and genitourinary tracts.

Ocular: Internal and external ophthalmoplegia; diminished lacrimation; amyloid deposits in conjunctival, episcleral, and ciliary vessels; vitreous opacities; amyloid deposits in the corneal stroma; retinal hemorrhages and perivascular exudates; paralysis of extraocular muscles; pseudopodia lentis; strabismus fixus convergens; keratoconus.

Clinical: Peripheral neuropathy (extremities); heart failure; defective hepatic and renal functions with hepatosplenomegaly; waxy skin lesions; muscular weakness (progressive); multiple myeloma; hoarseness; chronic gastrointestinal symptoms.

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