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Isotretinoin teratogen syndrome


Isotretinoin Teratogen Syndrome

General: Maternal ingestion of isotretin 212d38c oin (Accutane) during early pregnancy.

Ocular: Small palpebral fissures; deep orbits; systemic treatment with isotretinoin has been associated with blepharitis and conjunctivitis.

Clinical: Prominent forehead; low-set, small, undifferentiated ears; depressed nasal bridge; small chin.

Benke PJ. Isotretmoin teratogen syndrome. JAMA 1984; 24:3267-3269.




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