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Hansen disease (leprosy) 5


Hansen Disease (Leprosy) 5

General: Communicable disease caused by Mycobacterium leprae.

Ocular: Keratitis; leukoma; pannus; corneal ulcer; uveitis; iris atrophy; dacryocystitis; anisocoria; multiple pupils; decreased or absent pupillary reaction to light; paralysis of seventh nerve; episcleritis; blepharospasm; lagophthalmos; madarosis; secondary glaucoma; decreased intraocular pressure; subconjunctival fibrosis; punctate epithelial keratopathy; posterior subcapsular cataract; corneal hypesthesia; prominent corneal nerves; iridocyclitis; foveal avascular keratitis; scleritis; interstitial keratitis; iris pearls; dry eye.

Clinical: Disease affects primarily the skin, mucous membrane, and peripheral nerves.

Binford CH, et al. Leprosy. JAMA 1982; 247:16.

Dana MR. Ocular manifestations of leprosy in a noninstitutionalized community in the United States. Arch Ophthalmol 1994; 112:626-629.

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Hornblass A. Ocular leprosy in South Vietnam. Am J Ophthalmol 1973; 75:478.

Schwab IR, et al. Leprosy in a trachomatous population. Arch Ophthalmol 1984; 102:240-244.

Sekhar GC, et al. Ocular manifestations of Hansen's disease. Doc Ophthalmol 1994; 87:211-221.

Shields JA, et al. Ocular findings in leprosy. Am J Ophthalmol 1974; 77:880-890.




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