Guillain-barr syndrome (landry paralysis; acute infectious neuritis; acute polyradiculitis; acute febrile polyneuritis; acute idiopathic polyneuritis; inflammatory polyradiculoneuropathy; landry-guillain-barr-strohl syndrome; postinfectious polyneuritis)

General: Etiology unknown; occurs from age 16 to 50 years; Fisher syndrome is a variant (see Fisher Syndrome).

Ocular: Facial nerve paralysis with paralytic ectropion of the lower eyelid; mild-to-complete external ophthalmoplegia; optic neuritis; papilledema; ptosis; anisocoria; nystagmus; dyschromatopsia; scotoma; bilateral tonic pupils.

Clinical: Polyneuritis involving facial peripheral motor nerves and spinal cord; facial diplegia; bladder incontinence; variable degrees of paralysis, usually beginning in lower extremities; tendon reflexes absent; involvement of respiratory muscles possible; paresthesia (symmetrical).

Anzai T, et al. Guillain-Barre syndrome with bilateral tonic pupils. Int Med 1994; 33:248-251.

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Guillain GA. Sur un Syndrome de Radiculoneurite avec Hyperalbuminose du Liquide Cephalo-Rachidien sans Reaction Cellulaire. Remarques sur les Caracteres Cliniques et Graphiques des Reflexes Tendineux. Bull Mem Sec Med Hop (Paris) 1916; 40:1462.

Magalini SI, Scrascia E. Dictionary of Medical Syndromes. 2nd ed. Philadelphia: JB Lippincott, 1981.