Francois (2) dystrophy (francois-evens syndrome; speckled corneal dystrophy) 4

General: Etiology unknown; congenital; nonprogressive; autosomal dominant, but sporadic cases have been reported.

Ocular: Corneal dystrophy characterized by minute punctate opacities found in all layers of the cornea; varies in size, form, and degree of opacity but is identical in both eyes; anterior limiting membrane is always intact.

Bron AJ. The corneal dystrophies. Curr Opin Ophthalmol 1990; 1:333.

Francois J. Heredity in Ophthalmology. St. Louis: CV Mosby, 1961.

Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.