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Cooley anemia (thalassemia; thalassemia major; thalassemia minor) 294


Cooley anemia (thalassemia; thalassemia major; thalassemia minor)                                             294

Cooley Anemia (Thalassemia; Thalassemia Major; Thalassemia Minor)   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp;   &n 313d37d bsp; 294

General: Autosomal dominant in synthesis of the  or  chain of hemoglobin; most prevalent in Mediterranean and Oriental populations.

Ocular: Retinal hemorrhages; angioid streaks; macular vascular abnormalities; pigmented chorioretinal scars (black sunbursts); occlusion of peripheral retinal arteries; vitreous hemorrhages.

Clinical: Hemolytic anemia; hypochromic anemia.

Condon PI, Serjeant GR. Ocular findings in sickle cell thalassemia in Jamaica. Am J Ophthalmol 1972; 74: 1105-l109,

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Goldberg MF. Ophthalmologic manifestations of sickle cell thalassemia. Arch Intern Med 1971; 128:33-39.

O'Donnell BF, et al. Angioid streaks in beta thalassemia minor. Br J Ophthalmol 1991; 75:639,

Rinaldi M, et al. Ocular involvement correlated with age in patients affected by major and intermedia beta-thalassemia treated or not with desferrioxamine. Metab Pediatr Syst Ophthalmol 1993; 16:23-25.



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