B-k mole syndrome (familial atypical multiple mole melanoma syndrome; dns; dysplastic nevus syndrome)  149

General: Autosomal dominant.

Ocular: Ocular melanoma; metastasis to the anterior segment of the eye; occurs much less often than metastases to the choroid; iris nevi; choroidal nevi; conjunctival nevi.

Clinical: Many large, irregular, variable nevi predominantly occurring on the upper part of the trunk and extremities; atypical melanocytic hyperplasia; lymphocyte infiltration of the dermis and neovascularization; cutaneous melanoma (possible association).

Abramson DH, et al. B-K mole syndrome. Arch Ophthalmol 1980; 98:1397-l399.

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McCarthy JM, et al. Conjunctival and uveal melanoma in the dysplastic nevus syndrome. Surv Ophthalmol 1993; 37: 377-386.

Rodriguez-Sains RS. Ocular findings in patients with dysplastic nevus syndrome. Ophthalmology 1986; 93:661-665.

Rodriguez-Sains RS. Ocular findings in patients with dysplastic nevus syndrome. An update. Dermatol Clin 1991; 9:723-728.