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Arcus cornea (arcus senilis)


Arcus Cornea (Arcus Senilis)

General: Autosomal dominant; occurs earlier in blacks; frequen 838e45i tly associated with abnormal serum lipid levels, but may occur without any predisposing factors; more commonly associated with familial hypercholesterolemia.

Ocular: Arcus of cornea.

Clinical: Can be associated with Tangier disease, Norum disease, and homozygotes type II hyperlipoproteinemia; osteogenesis imperfecta ring resembling arcus seen.

Barchiesi BJ, et al. The cornea and disorders of lipid metabolism. Surv Ophthalmol 1991; 36:1-22.

MacAraez PVJ, et al. Arcus not so senilis. Ann Intern Med 1968; 68:345-354.

McKusick VA. Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders, 12th ed. Baltimore: The Johns Hopkins University Press, 1998.

Online Mendelian Inheritance in Man, OMIM. McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University and National Center for Biotechnology Information, National Library of Medicine, February 12, 2007. World Wide Web URL: https://www.ncbi.nlm.nih.gov/omim/.





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