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Agranulocytosis syndrome


Agranulocytosis Syndrome (Pernicious Leukopenia Syndrome; Schultz Syndrome; Agranulocytic Angina Syndrome; Malignant Neutropenia Syndrome) 323j94d 323j94d 323j94d 323j94d

General: Caused by hypersensitivity reaction to chemicals, drugs, and ionizing radiation; may be idiopathic; more frequent in adults; female (3:1) preponderance; acute onset.

Ocular: Scleral and conjunctival icterus; conjunctival hemorrhages; retinal hemorrhages.

Clinical: Swollen, painful joints; malaise; sore throat with mucous membrane ulceration; sepsis.

Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.

McCluskey HB. Corticotropin (ACTH) in treatment of agranulocytosis following sulfisoxazole therapy. J Am Med Assoc 152:232.

Schultz W. Uber Eigenartige Halserkrankungen. Dtsch Med Wochenschr 1922; 48: 1495.





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