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Torre-muir syndrome


Torre-Muir Syndrome

General: Multiple sebaceous gland tumors of nonglabr 545g62f ous skin and visceral malignancy (primarily colonic) and keratoacanthomas; like Torre syndrome but associated with keratoacanthomas; benign skin tumors accompany and sometimes precede development of internal visceral malignancy; autosomal dominant inheritance.

Ocular: Sebaceous cell carcinoma of lid; carcinoma of caruncle; keratoacanthomas; tumor of the meibomian gland.

Clinical: Visceral carcinoma of gastrointestinal tract, breast, and prostate.

Hauck RM, Manders EK. Familial syndromes with skin tumor markers. Ann Plast Surg 1994; 33:102-l11.

Jakobiec FA, et al. Unusual eyelid tumors with sebaceous differentiation in the Muir-Torre syndrome. Ophthalmology 1988; 95:1543-l548.

Jakobiec FA. Sebaceous adenoma of the eyelid and visceral, malignancy. Am J Ophthalmol 1974; 78:952.

Muir EG, et al. Multiple primary carcinomata of colon, duodenum and larynx associated with keratoacanthomata of the face. Br J Surg 1967; 54: 19l.

Narita H, et al. Muir-Torre syndrome. J Dermatol 1992; 19:105-l08.

Tillawi I, et al. Solitary tumors of meibomian gland origin and Torre's syndrome. Am J Ophthalmol 1987; 104: 179-l82.

Torre D. Multiple sebaceous tumors. Arch Dermatol 1968; 98:549.




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