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Plague (bubonic plague; pneumonic plague) 9


Plague (Bubonic Plague; Pneumonic Plague) 9

General: Infectious disease of animals (principally wild animals and rodents) that is transmitted through the bite of infected ectoparasites; causative agent is Yersinia pestis.

Ocular: Inflammatory infiltrate of lids; subconjunctival hemorrhages; chemosis; staphyloma of sclera; keratitis; corneal abscess; iridocyclitis; choroiditis.

Clinical: Abrupt onset; chills; fever; rapid, thready pulse; painful, enlarged lymph nodes in bubonic plaque; headache and productive cough in pneumonic plaque; meningitis; occasional patients infected with Y. pestis become septic and die with bacteremia without developing any detectable lymphadenitis (septicemic plague).



Kasper DL, et al., eds. Harrisons Principles of Internal Medicine, 16th ed. New York: McGraw-Hill, 2005.

Butler T. Yersinia species (including plague). In: Mandell GL, Douglas RG Jr, Benett JE, eds. Principles and Practice of infectious diseases, 3rd ed. New York: Churchill Livingstone, 1990: 1748-l756.

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Hull HF, et al. Septicemia plague in New Mexico. J Infect Dis 1987; 155:113-l18.




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