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Passow syndrome (bremer status dysraphicus; status dysraphicus syndrome; syringomyelia; syringobulbia)


Passow Syndrome (Bremer Status Dysraphicus; Status Dysraphicus Syndrome; Syringomyelia; Syringobulbia) 333i82d 333i82d 333i82d 333i82d 333i82d 333i82d

General: Congenital nonclosure of the neural tube; familial occurrence or may be sporadic; insidious onset in second to third decade of life.

Ocular: Enophthalmos; ptosis; rotatory nystagmus; heterochromia iridis; anterior uveitis; corneal anesthesia; neuroparalytic keratitis; paralysis of third, fifth, sixth, and seventh cranial nerves; Horner syndrome; anisocoria; papilledema; optic atrophy; zonular cataract (see Horner Syndrome).

Clinical: Anesthesia over area of first division of trigeminal nerve; facial hemiatrophy; facial nerve paralysis; muscular weakness; cervical ribs; kyphoscoliosis; spina bifida; unilateral numbness of fingers; loss of deep reflexes; insensitivity to pain and temperature in affected areas; neurogenic bladder.



Duke-Elder S, ed. System of Ophthalmology, vol. III, part 2. St. Louis: CV Mosby, 1976:1034.

Geeraets WJ. Ocular Syndromes, 3rd ed. Philadelphia: Lea & Febiger, 1976.

Mancall EL, McCormick PC. Syringomyelia. In: Rowland LP, ed. Merritts Textbook of Neurology, 9th ed. Baltimore: Williams & Wilkins, 1991:752-753.

Menkes JH, Till Kenneth. Syringomyelia. In: Menkes JH, ed. Textbook of child neurology, 5th ed. Baltimore: Williams & Wilkins, 1995:265-267.

Minzter RM, Buckley EG. Neurocranial defects with neuro-ophthalmic significance. In: Wright KW, ed. Pediatric Ophthalmology and Strabismus. St. Louis: Mosby, 1995:850.

Passow A. Status dysraphicus. Klin Monatsbl Augenheilkd 1935; 94:102.

Ropper AH, Martin JB. Syringomyelia. In: Isselbacher KJ, et al., eds. Harrisons Principles of Internal Medicine, 13th ed. New York: McGraw-Hill, 1994:2358.




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