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Glaucoma, goniodysgenesis (dysgenic glaucoma; steroid glaucoma)


Glaucoma, Goniodysgenesis (Dysgenic Glaucoma; Steroid Glaucoma)

General: Autosomal dominant; use of topical dexamethasone under the two-allele system; three genotypes; high, intermediate, and low; more prominent in blacks; mechanism may be related to morphologic changes in the trabecular meshwork.

Ocular: Glaucoma; cataracts.

Clinical: None.

Armaly MF. The heritable nature of dexamethasone induced ocular hypertension. Arch Ophthalmol 1966; 75:32-35.

Duane TD. Clinical Ophthalmology. Philadelphia: JB Lippincott, 1987.

McKusick VA. Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders, 12th ed. Baltimore: The Johns Hopkins University Press, 1998.

Online Mendelian Inheritance in Man, OMIM. McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University and National Center for Biotechnology Information, National Library of Medicine, February 12, 2007. World Wide Web URL: https://www.ncbi.nlm.nih.gov/omim/.




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