Glander syndrome

General: Serious infection caused by Malleomyces mallei; 838c23i no naturally acquired infections in United States since 1938; transmission from equine animals to man; caused by traumatic inoculations or inhalations; either acute, gangrenous, or chronic ulcerative; fatal usually in 7 to 10 days.

Ocular: Conjunctivitis; dacryocystitis; ulcerating granulomatous orbital lesions; photophobia; lacrimation.

Clinical: Systemic erythematous pustules; inhalation infection; fever; rigors; generalized myalgia lymphangitis; fatigue, headaches; pleuritic chest pain; diarrhea; lymphadenopathy; splenomegaly; mild leukocytosis; multiple subcutaneous and intramuscular abscesses (often arms and legs); visceral involvement, including pulmonary, pleural, skeletal, hepatic, splenic, meningeal, and intracranial.

Braunwald E, et al., eds. Harrisons principles o/internal medicine, 11th ed. New York: McGraw-Hill, 1987.

Howe C, et al. The pseudomaller group: a review. J Infect Dis 1971; 124:598.

Jackson AE, et al. Recrudescent melioidosis associated with diabetes ketoacidosis. Arch Intern Med 1972; 130:268.