Fetal Alcohol Syndrome 4
General: Dysgenesis in children born to alcoholic mothers; both sexes affected; onset from birth.
Ocular: Antimongoloid slant of lid fissures; lateral displacement of inner canthi; ptosis; epicanthi; strabismus; myopia; optic nerve hypoplasia; diffuse corneal clouding; iridocorneal abnormalities with central corneal edema; lens opacification; motility disorders.
Clinical: Growth retardation; delayed development (physical and intellectual); maxillary hypoplasia; micrognathia; large, low-set ears; abnormal motor function; irritability; microcephaly; cerebral nervous system dysfunctions; abnormal philtrum; flattened nasal bridge; cardiovascular defects; thin upper lip.
Chan T, et al. Ocular manifestations in fetal alcohol syndrome. Br J Ophthalmol 1991; 75:524-526.
Cook CS, et al. Fetal alcohol syndrome. Arch Ophthalmol 1987; 105:1576.
Edward DP, et al. Diffuse corneal clouding in siblings with fetal alcohol syndrome. Am J Ophthalmol 1993; 115: 484-493.
Tenbrinck MS, Buchin SY. Fetal alcohol syndrome. JAMA 1975; 232:1144.
Ulleland CN. The offspring of alcoholic mothers. Ann N Y Acad Sci 1972; 197:167.
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