Ewing Sarcoma (Ewing Syndrome)
General: Highly metastatic round cell tumor of bo 919c21j ne; most commonly involves long or trunk bones; metastasizes at high rate; usually occurs between ages 10 and 25 years; seen more frequently in males than in females.
Ocular: Exophthalmos; orbital hemorrhages; orbital necrosis; commonly found as the second malignancy in patients with hereditary retinoblastoma.
Clinical: Lytic bone destruction; pain; edema; slight fever.
Duane TD. Clinical Ophthalmology. Philadelphia: JB Lippincott, 1987.
Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.
Miller NR, ed. Walsh and Hoyt's Clinical Neuro-Ophthalmology, 4th ed. Baltimore: Williams & Wilkins, 1987.
Smith LM, Donaldson SS. Incidence and management of secondary malignancies in patients with retinoblastoma and Ewing's sarcoma. Oncology 1991; 5:135-l41.
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