Disseminated sclerosis (multiple sclerosis)  375

General: Disseminated demyelination affecting white matter of the brain, spinal cord, and optic nerves; etiology unknown.

Ocular: Nystagmus; ptosis; myokymia; optic atrophy; papillitis; optic neuritis; anisocoria; Argyll Robertson pupil; Marcus Gunn pupil; hippus, decreased or absent papillary reaction to light; periphlebitis; visual field defects; gaze palsy; paralysis of third or sixth nerve; uveitis; oscillopsia; Uhthoff symptom (reduction of visual acuity with exercise or ocular hyperthermia); pars itis; retinal venous sheathing; retinitis; granulomatous uveitis.

Clinical: Incoordination; paresthesia; spasticity; tic douloureux; urinary frequency and infections; progressive disability; paralysis; death.

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